Title

A Simple Entry to Fused N-Aryl 1,2-Thiazetidine-S-Oxides: Thermal Isomerisation to 1,4-Thiazine-S-Oxides and Nucleophilic Ring-Opening with Alcohols and Amines

Document Type

Article

Publication Date

1-1-1997

Abstract

We show that fused 1,2-thiazetidine-S-oxides can be produced in one step from readily available aryl sulfonylamines by cycloaddition with quadricyclane; these adducts undergo smooth rearrangement to fused 1,4-thiazines-S-oxides on heating, and can be ring-opened with alcohols to form cis-1,2-arylamino sulfinic esters and cis-1,2-arylamino sulfinamides on treatment with amines.

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