Green chemistry-assisted synthesis of CuO nanoparticles: Reaction optimization, DNA cleavage, and DNA binding studies
Document Type
Conference Proceeding
Publication Date
1-1-2020
Abstract
Copper nanoparticles show considerable antibacterial, anti-fungal and related effects in comparison with bulk CuO and have been explored for their biological applications. In this work green synthesis approach was adopted to synthesize CuONps utilizing Syzygium aromaticum bud extract. CuONps showed a sharp band around 298 nm in UV–Vis spectrum, affirming their formation. The average size of synthesized CuONps was inspected by Debye-Scherrer equation using PXRD spectrum and was found 70 nm. Interaction study of CuONps with Calf-Thymus DNA have been investigated which has given significant results. The CuONps have also shown 20% DNA cleavage activity against E.coli DNA.
Recommended Citation
De, A., Das, R., Jain, P., & Kaur, H. (2020). Green chemistry-assisted synthesis of CuO nanoparticles: Reaction optimization, DNA cleavage, and DNA binding studies. Retrieved from https://digitalcommons.pvamu.edu/arts-and-science-facpubs/14