Screening of antioxidant activities of bark of carica papaya l by different methods

Document Type

Article

Publication Date

1-1-2021

Abstract

In this study, we have investigated ethanolic extract of bark of Carica papaya L. to identify antioxidant activities by using different methods. The yield of bark extract was found to be 2.81% w/w after extraction. At first, DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radical scavenging assay was performed where the IC50 (inhibitory concentration) value of extract was 23.89 µg/ml and the IC50 value of ascorbic acid which is used as standard antioxidant was 12.9 µg/ml. The bark extract showed significant TPC (Total Phenolic Content) of 328.56 mg GAE/gm of dry extract by using Gallic acid calibration curve, TFC (Total Flavonoid Content) of 195.329 mg QE/gm of dry extract by using Quercetin calibration curve and TTC (Total Tannin Content) of 47.239 mg GAE /gm of dry extract by using Gallic acid calibration curve. The above study suggested that Carica papaya L. bark extract showed significant antioxidant activities which may play an important role in drug discovery from natural products.

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