Two new triterpene glycosides from centella asiatica

Document Type

Article

Publication Title

Planta Medica

Abstract

Phytochemical investigation of the leaves of Centella asiatica resulted in the isolation and characterization of eight triterpenes and/or saponins [which were characterized as 23-O-acetylmadecassoside (1), asiatic acid (2), madecassic acid (3), asiaticoside C (4), asiaticoside F (5), asiaticoside (6), madecassoside (7), and 23-O-acetylasiaticoside B (8)] together with sitosterol 3-O-β-glucoside (9), stigmasterol 3-Oβ-glucoside (10), and querectin-3-O-β-D-glucuronide (11). A new ursane-derived saponin (23-O-acetylmadecassoside) and a new oleanane-derived saponin (23-O-acetylasiaticoside B) were found as well. Structure elucidation was done by using spectroscopic techniques (HRESIMS, 1D and 2DNMR), chemical methods, and comparative literature studies. © Georg Thieme Verlag KG Stuttgart - New York.

First Page

1018

Last Page

1021

DOI

10.1055/s-0029-1240864

Publication Date

7-29-2010

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