The Influence Of The Adrenotrophic Hormone, Desoxycorticosteron, Cortisone And Adrenalin On The Cellular Elements Of The Blood And Adrenal Ascorbic Acid In The Albino Rat
Date of Award
Master of Science
Clinical and experimental data reported in recent years have indicated that there is a relationship between the activity of the adrenal cortex and the hematologic picture of an individual. Recent studies by Crafts et al.(1941) clearly point out that there is a relationship between the endocrine system and the cellular elements of the blood. Craft noted the following in adrenalectomized animals; increase in reticulocytes, decrease hemoglobin percentage, increase of the color index, but a normal white cell count.
The abnormalities that arise in an individual's hemogram have been noted in many pathological conditions of the endocrine system as well as in experimental analyses involving the endocrines. White et al. (1944) proved that injection of ACTH decreased the lymphocyte count in an individual but increased the number of polymorphonuclear leucocytes. These investigators proved that lymphopenia is a specific response to ACTH because it does not occur in the adrenalectomized animals treated with ACTH. Therefore, these experiments by White and other related ones clearly point out that ACTH plays an important role in the normal function of the adrenal gland.
Charles H. Nicholas
Charles H. Nicholas
Prairie View Agricultural and Mechanical College
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Date of Digitization
John B Coleman Library
City of Publication
Todd, Sr., F. D. (1958). The Influence Of The Adrenotrophic Hormone, Desoxycorticosteron, Cortisone And Adrenalin On The Cellular Elements Of The Blood And Adrenal Ascorbic Acid In The Albino Rat. Retrieved from https://digitalcommons.pvamu.edu/pvamu-theses/1083